Endocrine Disorder Practice Test

When blood glucose levels are very high, the kidneys can’t reabsorb all the glucose, so glucose spills into the urine and draws water with it. That osmotic diuresis leads to large amounts of urine and fluid loss, creating dehydration if the hyperglycemia isn’t treated. Dehydration from this mechanism can worsen the hyperglycemia by reducing renal blood flow and glucose clearance, and it can cause symptoms like thirst, rapid heart rate, and dizziness. Other options aren’t the most likely immediate problems: hypoglycemia is a low blood sugar issue, not a direct result of high glucose; edema is not a typical acute consequence of osmotic diuresis; hypertension isn’t expected from uncontrolled hyperglycemia.